Megadrive Processor Unit may refer to:
- Megadrive Processor Unit (Hyperdimension Neptunia Victory)
- Megadrive Processor Unit (Hyperdimension Neptunia Re;Birth1) (called Omega Drive in-game)
- Megadrive Processor Unit (Hyperdimension Neptunia Re;Birth3) (called Omegadrive in-game)
- Megadrive Processor Unit (Superdimension Neptune VS Sega Hard Girls) (called Omega Drive in-game)
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